Medicine Overview of Alatrol 10mg Tablet

Introduction
Alatrol 10 belongs to a group of medicines called antihistamines. It is used to treat various allergic conditions such as hay fever, conjunctivitis and some skin reactions, and reactions to bites and stings. It relieves watery eyes, runny nose, sneezing, and itching. Alatrol 10 can be taken with or without food. The dose required for you may vary depending on what you are taking it for. This medicine is usually taken in the evening but follow the advice of your doctor on how to take it. You may need this medicine only on days you have symptoms, but if you...
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Uses of Alatrol 10
  • Allergic conditions
Side effects of Alatrol 10
Common
  • Sleepiness
How to use Alatrol 10
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alatrol 10 may be taken with or without food, but it is better to take it at a fixed time.
How Alatrol 10 works
Alatrol 10 is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.
Quick Tips
  • Your doctor has prescribed Alatrol 10 to help relieve allergy symptoms such as itching, swelling, and rashes.
  • It's much less likely to make you feel sleepy than other similar medications.
  • It is okay to take Alatrol 10 with most other medications as it has few drug interactions.
  • Use caution while driving or doing anything that requires concentration as Alatrol 10 can cause dizziness and sleepiness.
  • Do not drink alcohol while taking Alatrol 10 as it may cause increased sleepiness.
  • Stop taking Alatrol 10 at least three days before taking an allergy test as it can affect the test results.
Brief Description
Indication
Allergic rhinitis, Hay fever, Allergies, Urticaria
Administration
May be taken with or without food.
Adult Dose
Oral Allergic conditions Adult: 10 mg once daily or 5 mg bid. Elderly: Initially, 5 mg once daily. Hepatic impairment: Initially, 5 mg once daily. Syrup: Adults: 2 teaspoon once daily or 1 teaspoon twice daily.
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Child Dose
Oral Allergic conditions Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses. Syrup: Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily. Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily. <2 years: Safety and efficacy not established
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Renal Dose
Renal impairment GFR >50 mL/min: Dose adjustment not necessary GFR ? 50 mL/min: 5 mg PO qDay Peritoneal dialysis: 5 mg PO qDay Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly
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Contraindication
Hypersensitivity; lactation.
Mode of Action
Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.
Precaution
Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy. Lactation: Excreted in breast milk; use not recommended
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Side Effect
>10% Somnolence (2-14%),Headache (11-14%) 1-10% Fatigue (5.9%),Dry mouth (5%),Dizziness (2%),Diarrhea (2-3%),Malaise (4%),Bronchospasm (2-3%),Vomiting (2-3%),Epistaxis (2-4%) <1% Stomach pain,Drowsiness,Angioedema,Fussiness,Hallucinations,Hypotension,Tremor,Tongue discoloration
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Pregnancy Category Note
Pregnancy There are no adequate and well-controlled studies in pregnant women Lactation Cetirizine has been reported to be present in human breast milk In mice and beagle dogs, studies indicated that cetirizine was excreted in milk When a drug is present in animal milk, it is likely it will be present in human milk
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Interaction
Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).
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