Cilosta Tablet

Category: Pharmacy
SKU: BEP_955893
Seller: Best Buy Pharma

Tk 12.09


Medicine Overview of Cilosta 100mg Tablet

Introduction
Cilosta 100 is used in the treatment of pain in legs due to insufficient blood flow (intermittent claudication). It also helps in reducing cramping, numbness, or weakness in the legs that occurs on walking in such patients. Cilosta 100 should be taken regularly as advised by the doctor. You should take it on an empty stomach and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor. It may cause side effects like headache, edema, nausea, diarrhea, dizziness and chest pain. Use of this medicine may increase your risk of bleeding. Let your doctor know...
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Uses of Cilosta 100
  • Intermittent claudication
Side effects of Cilosta 100
Common
  • Headache
  • Palpitations
  • Abnormal stool
  • Diarrhea
  • Dizziness
  • Chest pain
  • Loss of appetite
  • Bleeding
  • Rash
How to use Cilosta 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cilosta 100 is to be taken empty stomach.
How Cilosta 100 works
Cilosta 100 widens the blood vessels and decreases the stickiness of the platelets, thereby increasing the blood flow to the lower limbs.
What if you forget to take Cilosta 100?
If you miss a dose of Cilosta 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • Take it at least half an hour before or two hours after breakfast and dinner.
  • It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed.
  • Consult your doctor, if your symptoms do not improve after 4 weeks of treatment.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Do not take it if you have heart failure, persistent chest pain at rest, or have had a heart attack or any heart surgery in the last six months.
Brief Description
Indication
Peripheral vascular disease, Intermittent claudication
Administration
Should be taken on an empty stomach. Take at least ½ hr before or 2 hr after meals.
Adult Dose
Oral Peripheral vascular disease Adult: 100 mg bid. May reduce dose in patients taking enzyme inhibitors concurrently. Hepatic Impairment Moderate to severe: Use caution
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Renal Dose
Renal Impairment CrCl< 25 mL/min: Use caution
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Contraindication
Heart failure; known predisposition to bleeding; history of ventricular arrhythmias; QT interval prolongation; severe renal impairment; moderate to severe hepatic impairment.
Mode of Action
Cilostazol is a reversible, selective inhibitor of phosphodiesterase-III (PDE-III), thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. Increase in cAMP in platelets and blood vessels leads to inhibition of platelet aggregation and vasodilation. Cilostazol also inhibits adenosine uptake into cells, which augments the cAMP-elevating effect of PDE-III inhibition.
Precaution
Congestive heart disease. Concurrent therapy with clopidogrel has not been studied for safety or efficacy. Pregnancy and lactation. Lactation: Excretion in milk unknown; not recommended
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Side Effect
>10% Headache (27-34%),Diarrhea (12-19%),Abnormal stools (12-15%),Infection (10-14%),Rhinitis (7-12%),Pharyngitis (7-10%) 1-10% Dizziness (9-10%),Palpitations (5-10%),Peripheral edema (7-9%),Back pain (6-7%),Dyspepsia (6%),Abdominal pain (4-5%),Tachycardia (4%),Increased cough (3-4%),Myalgia (2-3%),Atrial fibrillation (<2%),CHF (<2%),MI (<2%),Hematemesis (<2%),Ecchymosis (<2%),Blood in eye (<2%),Epistaxis (<2%),Hemoptysis (<2%),Nausea Frequency Not Defined Decreased platelet aggregation,Agranulocytosis,Aplastic anemia,Leukopenia,Thrombocytopenia,Stevens-Johnson syndrome
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Pregnancy Category Note
Pregnancy category: C Lactation: Excretion in milk unknown; not recommended
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Interaction
Co-admin with drugs that affect CYP3A4 (erythromycin, other macrolides, diltiazem) or CYP2C19 (omeprazole) may influence the pharmacokinetics of cilostazol.
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