Picture of Dexlan-60mg Capsule
Picture of Dexlan-60mg Capsule

Dexlan-60mg Capsule

Category: Pharmacy
SKU: BEP_952155
Seller: Best Buy Pharma
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Medicine Overview of Dexlan 60mg Capsule

Introduction
Dexlan 60 is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and some other stomach conditions associated with excessive acid production. Dexlan 60 is also used to prevent stomach ulcers and acidity that may be seen with the prolonged use of pain-killers. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying...
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Uses of Dexlan 60
  • Gastroesophageal reflux disease (Acid reflux)
  • Peptic ulcer disease
Side effects of Dexlan 60
Common
  • Nausea
  • Abdominal pain
  • Flatulence
  • Diarrhea
  • Vomiting
How to use Dexlan 60
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Dexlan 60 is to be taken empty stomach.
How Dexlan 60 works
Dexlan 60 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
What if you forget to take Dexlan 60?
If you miss a dose of Dexlan 60, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • Dexlan 60 should be taken 1 hour before a meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use of Dexlan 60 can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Brief Description
Indication
Oesophagitis, Gastro-oesophageal reflux disease (GERD)
Administration
Capsule: May take with or without food DR: Take at least 30 minutes before a meal
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Adult Dose
Erosive Esophagitis Capsule: Indicated for healing of all grades of erosive esophagitis (EE) and maintaining healing of EE DR: Indicated for maintaining healing of EE Healing (capsule): 60 mg PO qDay for up to 8 weeks Maintenance (capsule or DR): 30 mg PO qDay for up to 6 months Gastroesophageal Reflux Disease Indicated for treating heartburn associated with symptomatic nonerosive GERD Capsule or DR: 30 mg PO qDay for 4 weeks Hepatic impairment Milde (Child-Pugh A): Dose adjustment not necessary Moderate (Child-Pugh B): Not to exceed 30 mg/day Severe (Child-Pugh C): Not recommended
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Child Dose
<12 years Safety and efficacy not established >12 years Erosive Esophagitis Capsule: Indicated for healing of all grades of erosive esophagitis (EE) and maintaining healing of EE DR: Indicated for maintaining healing of EE Healing (capsule): 60 mg PO qDay for up to 8 weeks Maintenance (capsule or DR): 30 mg PO qDay for up to 6 months Gastroesophageal Reflux Disease Indicated for treating heartburn associated with symptomatic nonerosive GERD Capsule or DR: 30 mg PO qDay for 4 weeks
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Contraindication
Hypersensitivity.
Mode of Action
R-enantiomer of lansoprazole; PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion.Dual release formulation.
Precaution
Hepatic impairment. Gastric malignancy should be ruled out. Pregnancy and lactation. Lactation Risk Summary There is no information regarding presence of dexlansoprazole in human milk, effects on breastfed infant, or on milk production; however, lansoprazole and its metabolites are present in rat milk; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and potential adverse effects on breastfed child from therapy or from the underlying maternal condition
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Side Effect
1-10% Diarrhea (5%),Abdominal pain (4%),Nausea (3%),URI (2-3%),Vomiting (1-2%),Flatulence (1%) <1% (Selected) Arrhythmia,Bradycardia,Barrett's esophagus,DVT,Dyspnea,Hepatomegaly,Hypertension,Paresthesia,Rectal hemorrhage,Vulvovaginal infection
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Pregnancy Category Note
Pregnancy There are no studies with dexlansoprazole use in pregnant women to inform a drug-associated risk; dexlansoprazole is R-enantiomer of lansoprazole, and published observational studies of lansoprazole use during pregnancy did not demonstrate an association of adverse pregnancy-related outcomes with lansoprazole In animal reproduction studies, oral administration of lansoprazole to rats during organogenesis through lactation at 1.8 times the maximum recommended human dexlansoprazole dose; produced reductions in the offspring in femur weight, femur length, crown-rump length and growth plate thickness (males only) on postnatal day 21; these effects were associated with reduction in body weight gain; advise pregnant women of...
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Interaction
Increased risk of hypomagnesaemia w/ diuretics and digoxin. May decrease plasma concentration of erlotinib, dasatinib and lapatinib. May decrease the bioavailability of itraconazole and ketoconazole. May increase plasma concentration of cilostazol and methotrexate. Reduced bioavailability w/ antacids and sucralfate. Potentially Fatal: May decrease serum levels and pharmacological effects of rilpivirine and atazanavir.
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