Picture of Dibenol 5 Tablet
Picture of Dibenol 5 Tablet

Dibenol 5 Tablet

Category: Pharmacy
SKU: BEP_955946
Seller: Best Buy Pharma
Tk 0.35
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Medicine Overview of Dibenol 5mg Tablet

Introduction
Dibenol is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness. Dibenol may be used by itself or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working....
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Uses of Dibenol
  • Type 2 diabetes mellitus
Side effects of Dibenol
Common
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Headache
  • Dizziness
How to use Dibenol
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dibenol is to be taken with food.
How Dibenol works
Dibenol is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.
What if you forget to take Dibenol?
You should skip a dose of Dibenol if a meal is skipped, and add a dose of medicine if you eat an extra meal.
Quick Tips
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Dibenol affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Brief Description
Indication
Type 2 DM
Administration
Should be taken with food. Take w/ breakfast or the 1st main meal of the day.
Adult Dose
Oral Type 2 diabetes mellitus Adult: Initially, 2.5-5 mg daily, may increase wkly by increments of 2.5-15 mg daily. Doses >10 mg daily should be given in 2 divided doses. Max: 20 mg daily. Elderly: Initially, 1.25 mg daily. Hepatic impairment: Severe: Contraindicated.
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Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: Severe: Contraindicated.
Contraindication
Severe or life-threatening hyperglycaemia, severe liver or renal failure, type 1 diabetes, diabetic ketoacidosis with or without coma, patients with severe infection or trauma.
Mode of Action
Glibenclamide lowers blood glucose concentration principally by stimulating secretion of endogenous insulin from the pancreatic beta-cells. Hypoglycaemic action associated w/ short-term therapy appears to include reduction of basal hepatic glucose production and enhancement of peripheral insulin action at target sites.
Precaution
Elderly; malnourished; mild to moderate renal and hepatic disorders. Impaired alertness. Avoid alcohol. Careful monitoring of blood-glucose concentration. Adrenocortical insufficiency. Changes in diet or prolonged exercise may also provoke hypoglycaemia. Increased risk of hypoglcaemia due to its long half-life. Avoid in severe hepatic impairment. Pregnancy, lactation. Lactation: Not known if crosses into breast milk; avoid use in nursing women
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Side Effect
Hypoglycaemia; cholestatic jaundice; agranulocytosis; aplastic anaemia; haemolytic anaemia. Blood dyscrasias (reversible), liver dysfunction, GI symptoms, allergic skin reactions. Potentially Fatal: Prolonged hypoglycaemia seen in elderly or debilitated patients with hepatic or renal diseases.
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Interaction
Serum levels may be reduced by colesevelam. May increase hypoglycaemic effect w/ MAOIs, chloramphenicol, fluoroquinolones (e.g. ciprofloxacin), probenecid, NSAIDs, ACE inhibitors, fluoxetine, disopyramide, clarithromycin, salicylates, sulfonamides, beta-blockers. Increased serum levels w/ antifungal antibiotics (e.g. miconazole, fluconazole). May decrease hypoglycaemic effect w/ nonthiazide (e.g. furosemide) and thiazide diuretics, corticosteroids, phenothiazines, thyroid agents, oestrogens, OC, phenytoin, nicotinic acid, sympathomimetic agents, rifampicin, Ca channel blockers, isoniazid. Potentially Fatal: May increase hepatotoxic effect of bosentan.
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