Picture of Flux 500mg Capsule
Picture of Flux 500mg Capsule

Flux 500mg Capsule

Category: OTC
SKU: BEP_955381
Seller: Best Buy Pharma
Tk 11.50
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Medicine Overview of Flux 500mg Capsule

Introduction
Flux 500 is an antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, skin and soft tissue, bones and joints and blood. Flux 500 is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do...
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Uses of Flux 500
  • Bacterial infections
Side effects of Flux 500
Common
  • Nausea
  • Vomiting
  • Diarrhea
  • Allergic reaction
  • Injection site reactions (pain, swelling, redness)
How to use Flux 500
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it.
How Flux 500 works
Flux 500 is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is needed for them to survive.
What if you forget to take Flux 500?
If you miss a dose of Flux 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • You have been prescribed Flux 500 for the treatment of bacterial infections.
  • It is given by an injection into a vein or muscle, or via a drip into a vein.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Brief Description
Indication
Pneumonia, Burns, Meningitis, Endocarditis, Sinusitis, Septicaemia, Tonsillitis, Surgical Prophylaxis, Staphylococcal skin infections, Boils, Osteomyelitis, Enteritis, Wounds, Abscesses, Infected eczema, Infected acne
Administration
Should be taken on an empty stomach. Take on an empty stomach ½-1 hr before meals. Reconstitution: Dissolve 250-500 mg in 5-10 mL water for inj or 1 g in 15-20 mL water for inj. For IV infusion, further dilute in suitable IV fluids (e.g. water for inj, NaCl 0.9%, glucose 5%, NaCl 0.18% w/ glucose 4%).
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Adult Dose
Adults (including elderly patients): Oral: 250-500mg 3-4 times a day. Intravenous IV 0.25-1 g 4 times/day, may double in severe cases. Up to 8 g/day in 3-4 divided doses may be given for osteomyelitis. Up to 8 g/day in 4 divided doses for endocarditis in patients weighing <85 kg and 12 g/day in 6 divided doses for patients weighing >85 kg.
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Child Dose
Children have been given doses of 12.5-25 mg/kg body weight 4 times a day. Intravenous 2-10 years: Half of adult dose Under 2 years: One fourth of adult dose
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Renal Dose
Renal impairment: CrCl (ml/min) <10 Dosage adjustment may be necessary.
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Contraindication
Hypersensitivity to penicillins. Porphyria.
Mode of Action
Flucloxacillin inhibits the 3rd and last step of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. It is active against penicillinase-producing and non-penicillinase-producing staphylococci.
Precaution
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Avoid contact, skin sensitization may occur. Monitor serum potassium concentration, renal and haematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route; elderly. Hepatic impairment.
Side Effect
Hypersensitivity reactions including urticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial nephritis; neutropenia; thrombocytopenia; CNS toxicity including convulsions; diarrhoea; antibiotic-associated colitis; hepatitis, cholestatic jaundice; agranulocytosis; phlebitis (IV infusion). Potentially Fatal: Anaphylaxis. Stevens-Johnson syndrome
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Interaction
May increase the risk of methotrexate toxicity. May decrease the efficacy of oestrogen-containing OC. Enhanced plasma concentrations w/ probenecid. Bacteriostatic drugs (e.g. chloramphenicol, tetracycline) may interfere w/ the bactericidal effect of flucloxacillin. May prolong bleeding time in patients on oral anticoagulants.
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