Picture of Lamitrin 25mg Tablet
Picture of Lamitrin 25mg Tablet

Lamitrin 25mg Tablet

Category: Pharmacy
SKU: BEP_950044
Seller: Best Buy Pharma
Tk 10.03
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Medicine Overview of Lamitrin 25mg Tablet

Introduction
Lamitrin 25 belongs to a group of medicines called anti-epileptics. It is used to treat two conditions, epilepsy and bipolar disorder. It works by blocking the signals in the brain that trigger epileptic seizures (fits) and in another way to prevent extreme mood swings. Lamitrin 25 can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get...
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Uses of Lamitrin 25
  • Epilepsy/Seizures
  • Bipolar disoder
Side effects of Lamitrin 25
Common
  • Skin rash
  • Headache
  • Nausea
  • Vomiting
  • Dryness in mouth
  • Insomnia (difficulty in sleeping)
  • Sleepiness
  • Dizziness
  • Back pain
  • Abdominal pain
  • Blurred vision
  • Double vision
  • Impaired coordination
  • Nasal congestion (stuffy nose)
  • Infection
How to use Lamitrin 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lamitrin 25 may be taken with or without food, but it is better to take it at a fixed time.
How Lamitrin 25 works
Lamitrin 25 is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
What if you forget to take Lamitrin 25?
If you miss a dose of Lamitrin 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may cause headaches. Drink plenty of water and take a suitable pain killer. Inform your doctor if it does not go away.
  • It may cause skin rash. Inform your doctor immediately if you notice a rash, itching and peeling of skin.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the frequency of seizure.
Brief Description
Indication
Epilepsy,—adjunctive therapy in patients aged 2 years and older: • partial-onset seizures. • primary generalized tonic-clonic seizures. • generalized seizures of Lennox-Gastaut syndrome Epilepsy,—monotherapy in patients aged 16 years and older Bipolar disorder
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Administration
May be taken with or without food.
Adult Dose
Oral Epilepsy Adult: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, increase the dose by a max of 50-100 mg every 1-2 wk to usual maintenance doses of 100-200 mg daily, as a single dose or in 2 divided doses. Some patients may require up to 500 mg daily. Adjunct in epilepsy Adult: With valproate: Initially, 25 mg on alternate days for 2 wk followed by 25 mg once daily for 2 wk; thereafter, increase by a max of 25-50 mg every 1-2 wk; usual maintenance doses: 100-200 mg daily...
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Child Dose
Oral Epilepsy Child: >12 yr: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, increase the dose by a max of 50-100 mg every 1-2 wk to usual maintenance doses of 100 -200 mg daily, as a single dose or in 2 divided doses. Some patients may require up to 500 mg daily. <12 yr: Not recommended. Adjunct in epilepsy Child: With valproate: Initially, 0.15 mg/kg once daily for 2 wk followed by 0.3 mg/kg once daily for 2 wk; thereafter, increase by a max of 0.3 mg/kg every 1-2 wk...
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Renal Dose
Renal impairment Use caution; may consider reduce the dose in significant renal impairment
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Contraindication
Hypersensitivity.
Mode of Action
Lamotrigine inhibits voltage-sensitive sodium channels, thereby stabilising neuronal membranes and consequently inhibiting pathological release of excitatory amino acids (e.g. glutamate and aspartate). These amino acids play a role in the generation and spread of epileptic seizures.
Precaution
Hepatic or renal impairment. Closely monitor patient. Monitor children's body wt. Advise patient to report any hypersensitivity reaction. Avoid abrupt withdrawal unless severe skin reactions have developed. May impair ability to drive or operate machinery. Pregnancy and lactation. Serious skin rashes, Blood Dyscrasias, Suicidal Behavior, Aseptic Meningitis can occur in both adult and pediatric population. Lactation: Distributed into human breast milk; caution advised
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Side Effect
>10% Dizziness (38%),Diplopia (26-30%),Headache (29%),Ataxia (22%),Blurred vision (16-20%),Rhinitis (11-15%),Somnolence (14%) 1-10% Insomnia (6-10%),Fatigue (8%),Chest pain (5%),Peripheral edema (2-5%),Suicidal ideation (2-5%),Dermatitis (2-5%),Dry skin (2-5%),Increased libido (2-5%),Rectal hemorrhage (2-5%),Weakness (2-5%),Agitation (1-5%),Dysarthria (1-5%),Edema (1-5%),Fever (1-5%),Migraine (1-5%),Abnormal thoughts (1-5%),Urinary frequency (1-5%),Tremor (4%) Frequency Not Defined Palpitations,Anxiety,Chills,Depression,Decreased memory,Emotional lability,Incoordination,Malaise,Seizure exacerbation,Vertigo,Pruritus,Rash,Amenorrhea,Hot flashes,Abdominal pain,Constipation,Diarrhea,Dyspepsia,Nausea,Vomiting,Arthralgia,Neck pain,Cough,Flu syndrome,Infection,Vaginitis,Nystagmus Potentially Fatal: Stevens-Johnson syndrome and toxic epidermal necrolysis.
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Interaction
Metabolism enhanced by enzyme-inducing drugs e.g. phenytoin, carbamazepine, phenobarbitone, primidone, rifampicin, ethinyloestradiol/levonorgestrel combination. Metabolism reduced by sodium valproate.
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