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Constipation
Magnesium hydroxide (400 mg/5 mL): 30-60 mL/day PO at bedtime or in divided doses
Acid Indigestion
Magnesium hydroxide (400 mg/5 mL): 5-15 mL PO q4hr; no more than 4 doses per 24-hour period
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Child Dose
Constipation
<2 years: Safety and efficacy not established
Suspension
2-6 years: 5-15 mL/day of regular-strength liquid PO at bedtime or in divided doses
6-12 years: 15-30 mL/day (400 mg/5 mL)
>12 years: 30-60 mL/day (400 mg/5 mL)
Acid Indigestion
Liquid
<12 years: Not recommended
>12 years: 5-15 mL (400 mg/5 mL) PO q4hr; no more than 4 doses per 24-hour period
Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.
Precaution
Colostomy, ileostomy; electrolyte imbalance. Monitor for toxicity in patients with impaired renal function. Pregnancy.
Lactation: Use in nursing mothers appears to be safe
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Side Effect
Abdominal cramping, Diarrhea, Electrolyte imbalance, Hypotension, Muscle weakness, Respiratory depression, Hypermagnesaemia (in patients with renal impairment). Paralytic ileus.
Interaction
Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.