Nebita 2.5 mg Tablet 1 pc

Category: Pharmacy
SKU: BEP_956144
Seller: Best Buy Pharma

Tk 7


Medicine Overview of Nebita 2.5 2.5mg Tablet

Introduction
Nebita 2.5 belongs to a group of medicines called beta-blockers. It is used to treat high blood pressure (hypertension), and heart failure. It also helps to prevent future heart attacks and stroke and to prevent migraine. Nebita 2.5 is also used to relieve the symptoms caused by an overactive thyroid gland. It may be prescribed alone or together with other medications. The dose and frequency depend on what you are taking it for and the severity of your condition. It may be taken empty stomach or with a meal, but take it regularly at the same time each day to...
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Uses of Nebita 2.5
  • Hypertension (high blood pressure)
Side effects of Nebita 2.5
Common
  • Nausea
  • Headache
  • Fatigue
  • Constipation
  • Diarrhea
  • Dizziness
  • Cold extremities
How to use Nebita 2.5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nebita 2.5 may be taken with or without food, but it is better to take it at a fixed time.
How Nebita 2.5 works
Nebita 2.5 is a beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood around the body.
Quick Tips
  • Nebita 2.5 lowers your blood pressure and makes it easier for your heart to pump blood around your body.
  • Lowering high blood pressure helps prevent stroke and heart attack.
  • It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
  • It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
  • Do not stop taking Nebita 2.5 suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.
Brief Description
Indication
Heart failure, Hypertension
Administration
May be taken with or without food.
Adult Dose
Oral Hypertension Adult: Initially, 5 mg once daily. May increase dose at intervals of 2 wk if needed. Max: 40 mg once daily. Elderly: >65 yr Initially, 2.5 mg once daily increased to 5 mg once daily if required. Oral Heart failure Adult: Initially, 1.25 mg once daily. May double dose every 1-2 wk if tolerated. Max: 10 mg once daily. Hepatic impairment 2.5 mg/day PO initially; increased cautiously
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Renal Dose
Renal impairment: CrCl <30 mL/min: Initially, 2.5 mg once daily. Maintenance: Increased to 5 mg once daily if required.
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Contraindication
Hepatic impairment, sick sinus syndrome, 2nd and 3rd degree heart block (without a pacemaker), history of asthma, metabolic acidosis, severe peripheral arterial disease, severe bradycardia, cardiogenic shock or decompensated heart failure, untreated phaeochromocytoma. Pregnancy and lactation.
Mode of Action
Nebivolol exhibits high selectivity for beta1-adrenergic receptors and has vasodilating activity due to a direct action on the endothelium, involving nitric oxide release. It lacks intrinsic sympathomimetic and membrane-stabilising activity.
Precaution
Patients w/ inadequate cardiac function, well-compensated heart failure, myasthenia gravis. Patients undergoing major surgery involving general anaesth. May mask signs and symptoms of hypoglycaemia and hyperthyroidism. Abrupt withdrawal may exacerbate angina symptoms and/or precipitate MI and ventricular arrhythmias in patients w/ coronary artery disease. Pregnancy and lactation. Monitoring Parameters Monitor ECG, BP and blood glucose in diabetic patients. Lactation: Not known whether drug is excreted into breast milk; use not recommended
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Side Effect
1-10% Headache (6-9%),Fatigue (2-5%),Dizziness (2-4%),Diarrhea (2-3%),Nausea (1-3%),Increased triglyceride levels and insulin resistance, decreased high-density lipoprotein (HDL) levels (1%),Insomnia (1%),Peripheral edema (1%),Weakness (1%) <1% Bradycardia.Chest pain,Dyspnea Potentially Fatal: Anaphylaxis.
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Interaction
Increased plasma concentrations w/ potent CYP2D6 inhibitors (e.g. paroxetine, fluoxetine, propafenone, thioridazine, quinidine). Concomitant use w/ antiarrhythmic drugs (e.g. amiodarone, disopyramide) or nondihydropyridine Ca channel blockers (e.g. diltiazem, verapamil) may cause conduction disturbance. Additive negative effects on AV conduction and heart rate w/ other beta-adrenergic blocking agents or digoxin. Concurrent admin w/ catecholamine-depleting agents (e.g. reserpine) may result in additive hypotension or bradycardia. Abrupt withdrawal of clonidine may increase risk of rebound HTN.
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