Picture of Nofiate Capsule
Picture of Nofiate Capsule

Nofiate Capsule

Category: Pharmacy
SKU: BEP_952436
Seller: Best Buy Pharma
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Medicine Overview of Nofiate 200mg Capsule

Introduction
Nofiate 200 is a medicine used to treat high cholesterol. This medicine helps by lowering triglycerides and "bad" cholesterol (LDL), while at the same time raising the levels of "good" cholesterol (HDL). Lowering cholesterol levels reduces the risk of heart attack and stroke. Nofiate 200 should be taken in the dose and duration as advised by the doctor. You can take it at any time of day with food but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but if you stop taking this medicine, your condition could get...
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Uses of Nofiate 200
  • High triglycerides
  • High cholesterol
Side effects of Nofiate 200
Common
  • Increased liver enzymes
  • Nausea
  • Vomiting
  • Flatulence
  • Abdominal pain
  • Diarrhea
How to use Nofiate 200
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nofiate 200 is to be taken empty stomach.
How Nofiate 200 works
Nofiate 200 is a lipid lowering medication. It works by lowering the levels of triglycerides and "bad" cholesterol (LDL), while raising the levels of "good" cholesterol (HDL).
What if you forget to take Nofiate 200?
If you miss a dose of Nofiate 200, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • It should be taken with food.
  • Avoid alcohol consumption while taking this medication.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin or dark urine.
  • Inform your doctor if you experience muscle pain, tenderness, cramps, or weakness while taking Nofiate 200, particularly if it is accompanied by a fever.
  • Do not discontinue Nofiate 200 without consulting your doctor even if you feel better.
Brief Description
Indication
Hyperlipidemia, Hypercholesterolaemia, Hypertriglyceridaemia
Administration
Should be taken with food.
Adult Dose
Oral Hypercholesterolemia, Mixed dyslipidemia, Hypertriglyceridemia Tablet: 40-160mg once daily. Capsule: 200mg once daily. Hepatic impairment: Contraindicated.
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Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment Mild-Moderate: Initial: lower dose Severe: contraindicated
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Contraindication
Hypersensitivity; severe hepatic and renal impairment. Unexplained persistent liver function abnormality and primary biliary cirrhosis; preexisting gall bladder disease. Pregnancy, lactation.
Mode of Action
Fenofibrate, a fibric acid derivative, lowers plasma triglyceride by activating lipoprotein lipase thus increasing catabolism of VLDL w/ consequent increase in HDL levels.
Precaution
Renal or hepatic impairment. Monitor LFTs and blood counts regularly. Increased risk of cholelithiasis, pancreatitis, skeletal muscle effects. Withdraw treatment if no adequate response after 2 mth of treatment at max recommended dose. Lactation: Unknown if excreted in breast milk; not recommended
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Side Effect
1-10% Abdominal pain (4.6%),Back pain (3.4%),Increased AST (3.4%),Headache (3.2%),Increased ALT (3%),Increased CPK (3%),Nausea (2.3%),Constipation (2.1%) Potentially Fatal: Hepatitis, cholecystitis.
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Pregnancy Category Note
Pregnancy Limited available data with fenofibrate use in pregnant women are insufficient to determine a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes Animal data In animal reproduction studies, no evidence of embryo-fetal toxicity was observed with oral administration in rats and rabbits during organogenesis at doses less than or equivalent to the maximum recommended clinical dose of 120 mg daily, based on body surface area (mg/m2) Adverse reproductive outcomes occurred at higher doses in presence of maternal toxicity; drug should be used during pregnancy only if potential benefit justifies potential risk to fetus Lactation...
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Interaction
Decreased absorption w/ bile acid sequestrants (e.g. colestyramine). May increase risk of ciclosporin-induced nephrotoxicity. Increased risk of muscle toxicity w/ HMG-CoA reductase inhibitors (e.g. simvastatin). May increase risk of bleeding w/ oral anticoagulants.
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