Picture of Sardopa 250mg Tablet
Picture of Sardopa 250mg Tablet

Sardopa 250mg Tablet

Category: Pharmacy
SKU: BEP_952458
Seller: Best Buy Pharma
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Medicine Overview of Sardopa 250mg Tablet

Introduction
Sardopa 250 is a medicine used in the treatment of high blood pressure (hypertension). Lowering the blood pressure helps prevent future heart attack and stroke. This medicine is also used to treat high blood pressure during pregnancy. Sardopa 250 can be taken alone or in combination with other medicines. It can be taken with or without food. You may take it at any time of day but try to take it at the same time each day. You should take this medicine as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high...
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Uses of Sardopa 250
  • Hypertension (high blood pressure)
Side effects of Sardopa 250
Common
  • Dizziness
  • Fatigue
  • Sleepiness
  • Dryness in mouth
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
How to use Sardopa 250
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sardopa 250 may be taken with or without food, but it is better to take it at a fixed time. Avoid Sardopa 250 with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
How Sardopa 250 works
Sardopa 250 is an alpha-2 agonist. It works by relaxing blood vessels which makes the heart more efficient at pumping blood around the body.
What if you forget to take Sardopa 250?
If you miss a dose of Sardopa 250, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
  • For best results, take Sardopa 250 at the same time every day. Take last dose of the day at bedtime.
  • May cause dizziness and lightheadedness. If this happens to you, do not drive or use machinery.
  • Your doctor may monitor liver function. Inform your doctor if you notice yellowing of the skin or whites of the eyes, abdominal pain, nausea and vomiting while taking this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not discontinue use without consulting your doctor even if you feel better.
Brief Description
Indication
Hypertension
Administration
May be taken with or without food.
Adult Dose
Oral Hypertension Adult: Monotherapy: Initially, 250 mg bid-tid for 2 days; adjust at intervals of at least 2 days according to response. Maintenance: 500-2,000 mg daily. Max: 3,000 mg daily. Combination therapy: Initial dose should not exceed 500 mg daily in divided doses. Elderly: Initially, 125 mg bid; gradually increase according to response. Max: 2,000 mg daily.
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Child Dose
Oral Hypertension Child: <12 yr Initially, 10 mg/kg or 300 mg/m2 daily in 2-4 divided doses; adjust at intervals of at least 2 days according to response. Max: 65 mg/kg, 2,000 mg/m2 or 3,000 mg daily, whichever is least.
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Renal Dose
Renal Impairment Adjust dosage frequency with renal impairment CrCl >50 mL/min: q8hr CrCl 10-50 mL/min: q8-12hr CrCl <10 mL/min: q12-24hr
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Contraindication
Active liver disease (e.g. acute hepatitis, active cirrhosis) or depression. Concomitant use w/ MAOIs.
Mode of Action
Methyldopa stimulates alpha 2-adrenoceptors which results in reduced sympathetic tone and fall in BP.
Precaution
Patient w/ history of haemolytic anaemia, liver disease or depression; parkinsonism, hepatic porphyria. Not intended for the treatment of phaeochromocytoma. Renal or hepatic impairment. Childn, elderly. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor BP, blood counts, liver enzymes; direct Coombs' test. Lactation: distributed in breast milk but not in clinically significant amounts; compatible w/ breastfeeding
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Side Effect
Drowsiness, orthostatic hypotension, nausea, headache, weakness, fatigue, decreased libido, impotence, impaired concentration and memory, mild psychoses, depression, disturbed sleep, nightmares, paraesthesias, Bell's palsy, parkinsonism, involuntary choreoathetotic movements, oedema, fluid retention, exacerbation of angina pectoris, bradycardia, syncope, prolonged carotid sinus hypersensitivity, paradoxical HTN, GI disturbances (e.g. nausea, vomiting, diarrhoea, constipation), black/sore tongue, inflamed salivary glands, dry mouth, fever, eosinophilia, liver function disturbances, hepatitis, lupus-like syndrome, rashes, lichenoid and granulomatous eruptions, toxic epidermal necrolysis, flu-like syndrome, nocturia, uraemia, nasal congestion, retroperitoneal fibrosis, hyperprolactinaemia, breast enlargement (including gynaecomastia), galactorrhoea, amenorrhoea. Rarely, pancreatitis and colitis, immune thrombocytopenia, reversible leucopenia (primarily granulocytopenia). Potentially Fatal: Hepatic...
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Interaction
Reduced hypotensive effects with phenothiazines, TCAs and possibly, amphetamines. Additive hypotensive effects with levodopa; psychosis may also occur. Reduced absorption and effects with oral iron preparations. Reduced doses of general anaesthetics may be required. Effect of ephedrine may be reduced. Potentially Fatal: Increased risk of severe hypertension with MAOIs. Increased lithium toxicity
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