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Vildapin 50 is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness. Vildapin 50 is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It can be taken with or without food. The dose will depend on your condition and blood sugar levels. Therefore, you should use it...
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Uses of Vildapin 50
Type 2 diabetes mellitus
Side effects of Vildapin 50
Common
Headache
Common cold
Cough
Constipation
Dizziness
Sweating
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
How to use Vildapin 50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vildapin 50 may be taken with or without food, but it is better to take it at a fixed time.
How Vildapin 50 works
Vildapin 50 is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.
What if you forget to take Vildapin 50?
If you miss a dose of Vildapin 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Vildapin 50 should be taken at the same time every day since this helps you remember to take it.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Be careful while driving or operating machinery until you know how Vildapin 50 affects you.
Your doctor may check your kidney and liver function before starting treatment and regularly thereafter. Inform your doctor if you develop symptoms such as abdominal pain, fatigue, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
Brief Description
Indication
Type 2 DM
Administration
May be taken with or without food.
Adult Dose
Oral
Type 2 diabetes mellitus
Adult: 50 mg bid. Not recommended to use >100 mg/day.
W/ metformin or a thiazolidinedione: 50 mg twice daily; w/ a sulfonylurea: 50 mg/day in the morning.
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Renal Dose
Renal impairment: Moderate, severe and ESRD: 50 mg once daily.
Contraindication
Hypersensitivity to vildagliptin
Mode of Action
Vildagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycaemic control by preventing DPP-4 from inactivating the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, thus prolonging incretin activity in response to ingestion of nutrients. This increases insulin sensitivity, decreases glucagon secretion and improves ?-cell function.
Precaution
Patient w/ cardiac failure (NYHA functional class IV), type 1 DM; history of acute pancreatitis. Not intended for the treatment of diabetic ketoacidosis. Hepatic impairment, including patients w/ pre-treatment ALT or AST >3 times the upper limit of normal (ULN). Moderate or severe renal impairment, ESRD. Monitoring Parameters Monitor liver function.