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Xyril 25 is an antihistamine used to treat symptoms of skin allergy like itching, swelling, and rashes. It is also used to treat anxiety and helps to get relaxed before or after surgery. Xyril 25 should be taken with or without food, but take it at the same time every day to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long...
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Uses of Xyril 25
Anxiety
Side effects of Xyril 25
Common
Sedation
Nausea
Vomiting
Upset stomach
Constipation
Diarrhea
Loss of appetite
How to use Xyril 25
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xyril 25 may be taken with or without food, but it is better to take it at a fixed time.
How Xyril 25 works
Xyril 25 is an antihistaminic medication. In allergy, it works by blocking the action of a chemical messenger (histamine). This relieves allergy symptoms such as itching, swelling, and rashes. In short-term anxiety, it works by decreasing the activity in brain, thereby helping you feel relaxed/sleepy.
What if you forget to take Xyril 25?
If you miss a dose of Xyril 25, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
You have been prescribed Xyril 25 to treat allergy symptoms such as such as itching, swelling, and rashes or relieve/treat mild anxiety.
May decrease your alertness. Avoid driving or using machinery if this happens to you.
Avoid drinking alcohol when taking the Xyril 25, as it may cause excessive sleepiness or drowsiness.
Inform your doctor if you have a heart disease as Xyril 25 may increase the risk of heart problems.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Brief Description
Indication
Pruritus, Allergic conditions, Generalized anxiety disorder, Psychoneurosis, Chronic urticaria, Atopic or contact dermatoses, Pre- or post-operative sedation
Administration
May be taken with or without food.
Adult Dose
Oral
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested:
Adult: 50-100 mg 4 times daily.
For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus:
Adult: Initially, 25 mg at night increased if required up to 25 mg 3-4 times daily.
As a sedative when used as a premedication and following general anesthesia:
Adult: 50-100 mg.
Hepatic impairment: Reduce total daily dose by 33%.
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Child Dose
Oral For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested Children under 6 years: 50 mg daily in divided doses >6 years: 50 to 100 mg daily in divided doses. For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus Child: 6 mth to 6 yr Initially, 5-15 mg/day, increased to 50 mg/day in divided doses; >6 yr Initially, 15-25 mg/day, increased up to 50-100 mg/day in divided doses. As a sedative...
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Renal Dose
Renal Impairment
>50 mL/min: Dose adjustment not necessary
<50 mL/min: Administer 50% normal dose
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Contraindication
Porphyria, neonates, pregnancy, lactation.
Mode of Action
Hydroxyzine, a piperazine derivative, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and resp tract. It is a sedating antihistamine w/ antimuscarinic and significant sedative properties. It also possesses skeletal muscle relaxing, bronchodilator, antiemetic and analgesic properties.
Precaution
Renal and hepatic impairment; narrow-angle glaucoma; epilepsy; prostatic hypertrophy; bladder neck obstruction; asthma; COPD. May impair ability to drive or operate machinery.
Lactation: Excretion in milk unknown; use with caution
Additive or may potentiate CNS depressant effects of opiates or other analgesics, barbiturates or other sedatives, and anaesth. MAOIs and TCAs potentiate antimuscarinic effects.